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Immunopharmacological aspects in studying the mast cells

By Popivanova Galina Andreevna

Abstract

The work is aimed at studying the role of the mast cells in the reactions of the immunity of the mastocytes receptor apparatus, and at the possibility of the pharmacological regulation of the degranulation and rosette-formation phenomena. The modulating influence of the mast cells on the flow of some reactions of the immunity has been established; for the first time, the presence of the specific pharmacological and immunological receptors on the membrane of the mast cells. A method of the primary evaluation of the allergic status of the man organism, having the diagnostic importance and allowing to perform the purposeful antiallergic therapy, has been created. The results of the work have been introduced in the clinic hospital in Perm (allergological department) as well as in the curriculum of the Perm State Medical Institute and in the Central Scientific Research Laboratory. The developed method of the primary evaluation of the organism gives a possibility to reveal the allergization of the organism to use the purposeful antialergic therapy, reducing in such a way number of patients with the allergic diseasesAvailable from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio

Topics: 06V - Genetics, cytology, molecular biology, BIOLOGY
Year: 1992
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Provided by: OpenGrey Repository
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