The work covers the recombination genum SV40(brd) and eukaryota cells. The aim is to investigate the expression of the non-natural synthetic short nucleotide sequence coding the physiologically active bradikinin peptide in the eukaryota cells. The genic-engineering construction on base of DNA of SV40 virus which can be serve as a model for study of expression in the short nucleotide sequences has been developed. The recombination genum SV40(brd) providing a high expression level of the bradikin "gene" in the cells of the mammals without virus-helper has been made firstly. The system for testing of the bradikinin on the cardiomyocyte culture of the new-born rats has been developed. Application field: molecular and medical genetics, phisiologyAvailable from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio
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