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THE INFLUENCE OF MODIFICATION OF CYTOCHROME P450 2B4 WITH AMBER ANHYDRIDE ON INTERMOLECULAR INTERACTIONS IN THE SYSTEM MICROSOMAL MONOOXYGENASE

By Tatiana Vladimirovna Knyushko

Abstract

The kinetic parameters of interaction of subunits of cytochrome P450 and its interaction with NADPN-cytochrome P450 with reductase have been obtained, the succinylated preparations of cytochrome P450 have been received. It has been shown, that the free amino groups of cytochrome P450 do not take part directly in the processes of its aggregations, but they are necessary for the formation of the complexes of cytochrome P450 with MADPN-cytochrome P450 with the reductaseAvailable from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio

Topics: 06V - Genetics, cytology, molecular biology, CHEMISTRY
Year: 1996
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Provided by: OpenGrey Repository
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