Skip to main content
Article thumbnail
Location of Repository

THE CLINICO-BIOCHEMICAL AND EXPERIMENTAL STUDY OF THE DEGREE OF GLYCOSILATING OF GLYCOPROTEINS OF THE BLOOD SERUM AND ITS FUNCTIONAL IMPORTANCE

By Nataliya Mikhailovna Shilina and Russian Academy of Medical Sciences (Russian Federation) The Research Institute of Nutrition

Abstract

The purpose of the work: to examine the variations of the degree of the blood serum glycoproteins glycosilating at the different physiological and pathological states and to evaluate the functional role of the glycan chains of these proteins. It has been established, that the degree of glycosilating of the sum glycoproteins and transferrine of the premature children and children with hypotrophy is being increased. The law variation of the structure of the blood orosomucoid glycan chains has been proved. It has been established, that growth-stimulating and antioxidant activity of transferrine in vitro depends on the degree of the its sialating. The presentation about the relative independence of regulating of metabolism of the glycan and polypeptide chains of glycoproteins has been formulated. Developed and introduced in operation of the Institute has been electrophoretic method of determination of the content and degree of glycosilating of the blood serum transferrine. The obtained data can be used for the justification of selection of the additional prognostic tests at the evaluation of heaviness of hypotrophy and prematurely born children.Available from VNTIC / VNTIC - Scientific & Technical Information Centre of RussiaSIGLERURussian Federatio

Topics: 06P - Physiology, 06L - Medical equipment, hospital equipment, medical diagnostic equipment, BLOOD SERUM, GLYCOPROTEIN, CHILDREN, GLYCOSILATING, HYPOTROPHY, PREGNANT WOMEN
Year: 1997
OAI identifier:
Provided by: OpenGrey Repository
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://hdl.handle.net/10068/33... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.