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Assessment of lead exposure in schoolchildren from Jakarta.

By I Heinze, R Gross, P Stehle and D Dillon


Children attending schools in urban areas with high traffic density are a high risk group for lead poisoning. We assessed the magnitude of lead exposure in schoolchildren from Jakarta by analyzing blood lead concentrations and biomarkers of heme biosynthesis. A total of 131 children from four public elementary schools in Jakarta (two in the southern district and two in the central district) were enrolled in the study. To evaluate lead pollution in each area, soil samples and tap water were collected. The mean blood lead concentration was higher in the central district than in the southern district (8.3 +/- 2.8 vs. 6.9 +/- 3.5 microg/100 ml; p<0.05); 26.7% of the children had lead levels greater than 10 microg/100 ml. In 24% of the children, zinc protoporphyrin concentrations were over 70 micromol/mol hemoglobin; in 17% of the samples, hemoglobin was less than 11 g/100 ml. All other values were within the physiological range. Blood lead concentration and hematological biomarkers were not correlated. Analyses of tap water revealed lead values under 0. 01 mg/l; lead contamination of soil ranged from 77 to 223 ppm. Our data indicate that Indonesian children living in urban areas are at increased risk for blood lead levels above the actual acceptable limit. Activities to reduce pollution (e.g., reduction of lead in gasoline) and continuous monitoring of lead exposure are strongly recommended

Topics: Research Article
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Provided by: PubMed Central

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  2. (1980). Blood lead concentrations in a remote Himalayan population.
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  4. Blood lead levels in South African inner-city children. Environ Health Perspect94:125-130(1991).
  5. Childhood lead poisoning in Africa: a growing public health problem.
  6. (1996). Detection of iron-deficiency anemia in hospitalized patients by zinc protoporphyrin.
  7. (1971). Elemental Composition of Surficial Materials in the Conterminous United States: An Account of the Amounts of Certain Chemical Elements
  8. Environmental exposure to lead and children's intelligence at the age of seven years. The Port Pirie Cohort Study.
  9. Goldberg A,Yeung-Laiwah AA. Lead effects on the heme biosynthetic pathway. Relationship to toxicity.Ann NYAcad Sci 514:191-203(1987).
  10. Heavy metal levels in acculturated and unacculturated populations.
  11. (1994). Lead concentration in tap water and in blood of selected schoolchildren in southern Saxonia. Toxicol Lett72:325-331
  12. (1356). Lead exposure and child behavior.
  13. Lead exposure in early life: health consequences.
  14. Lead toxicity: current concerns.
  15. Low-level lead exposure and children's IQ: a meta-analysis and search for a threshold. Environ Res65:42-55(1994).
  16. (1985). Metabolic and cellular effects of lead. A guide to low level lead toxicity in children. Dietary and environment lead. In: Human Health Effects. Topics in Environmental Health,
  17. Okologische Bleibelastung und &quot;normale&quot; Blut-Bleiwerte der Bevolkerung: derzeitiger Sachstand. Zbl Arbeitsmed 37:2-8(1988).
  18. (1997). Pathways of lead exposure in urban children.
  19. (1993). Perspectives of lead toxicity.
  20. (1991). Preventing Lead Poisoning in Young Children. Atlanta, GA:Centers forDisease Control,
  21. (1995). Quantitative evaluation of heme biosynthesis pathway parameters as biomarkers of low-level lead exposure in rats.
  22. (1993). Reference intervals for blood lead and evaluation of zinc protoporphyrin as a screening test for lead toxicity.
  23. (1988). Threshold effect in lead-induced peripheral neuropathy.
  24. (1982). Threshold for lead damage to heme synthesis in urban children.
  25. Vehicular traffic as a determinant of blood lead levels in children: a pilot study in Mexico city.

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