Skip to main content
Article thumbnail
Location of Repository

Brainstorm: Structural brain abnormalities in schizophrenia and depression

By P.C.M.P. Koolschijn

Abstract

In this thesis a variety of magnetic resonance imaging (MRI) studies in schizophrenia and major depressive disorder are described. The importance of genetic research by means of twin models, or the search for candidate genes and relating them to brain morphometry is highlighted. Furthermore, evidence is provide to show the importance of longitudinal (MRI) studies when investigating age-related changes or the confounding influences of antipsychotic medication on brain morphometry. In addition, the combination of different MRI techniques such as cortical thickness measurements and voxel-based morphometry can provide a better understanding of what is going on in the brain, not only cortical but also subcortical. Finally, the application of meta-analytic methods in MRI research increases our knowledge of which brain structures are affected, and shows the path to which future research should be directed

Publisher: Utrecht University
Year: 2009
OAI identifier: oai:dspace.library.uu.nl:1874/35871
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://dspace.library.uu.nl:80... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.