In these lectures, which are written at an elementary and pedagogical level, we
discuss general aspects of (single) instantons in SU(N) Yang-Mills theory, and then
specialize to the case of N = 4 supersymmetry and the large N limit. We show how
to determine the measure of collective coordinates and compute instanton corrections
to certain correlation functions. We then relate this to D-instantons in type IIB supergravity.
By taking the D-instantons to live in an AdS5 × S5 background, we perform
explicit checks of the AdS/CFT correspondence
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