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The role of fimbriae of Escherichia coli in urinary tract infections

By 成明 石川


1)腎盂腎炎患者由来株では膀胱炎患者由来株よりもP線毛保有率が高かった.2) P線毛保有菌の大部分は1型線毛も有していた.3) P線毛保有菌は1型線毛保有菌よりも尿路上皮細胞に親和性が高かった.4)いずれの型の線毛保有菌も腎盂,尿管,膀胱上皮細胞ではその親和性に差はみられなかったThe incidence of P-fimbriated E. coli from patients with pyelonephritis, cystitis and asymptomatic bacteriuria was 78.6%, 31.9% and 22.2%, respectively. Almost all of the P-fimbriated E. coli have also type-1 fimbriae. In the in vitro test, P-fimbriated E. coli attached to the uroepithelial cells in higher number than the type 1 fimbriated E. coli. The results of the adhesion inhibition test suggested that simultaneous presence of P-and type 1 fimbriae is the most significant virulence factor in urinary tract infections

Topics: E. coli, P fimbriae, Type 1 fimbriae, 494.9
Publisher: 泌尿器科紀要刊行会
Year: 1991
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