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Calcium and stimulus-secretion coupling in the mast cell: stimulant and inhibitory effects of calcium-rich media on exocytosis

By W. W. Douglas and M. Kagayama


1. Isolated rat peritoneal mast cells incubated in Ca-free media for 2 h, with or without EDTA, and observed by phase-contact microscopy, became `bubbled' in appearance when subsequently exposed to media rich in calcium (16-110 mM)

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