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Non-volatile fatty acids in the diagnosis of non-specific vaginitis.

By C A Ison, C S Easmon, S G Dawson, G Southerton and J W Harris


In the vaginal washings of 100 women with symptomatic non-specific vaginitis a succinate/lactate ratio of greater than or equal to 0.4 had a diagnostic sensitivity of 80%, a specificity of 83% for this condition. The predictive value of a positive test was 94%, but that of a negative test was only 55%. A strong association between the presence of Gardnerella vaginalis, anaerobes, a vaginal pH of above 4.5, and amines was found not only in non-specific vaginitis, but also in trichomonal and gonococcal infection. A variety of primary changes may encourage the multiplication of both gardnerellae and anaerobes and their presence in non-specific vaginitis may be a secondary rather than a primary event

Topics: Research Article
Year: 1983
DOI identifier: 10.1136/jcp.36.12.1367
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Provided by: PubMed Central
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