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Effects of 4-aminopyridine in myasthenia gravis.

By H Lundh, O Nilsson and I Rosén

Abstract

A new drug, 4-aminopyridine, was prepared for use in humans and tested by repeated injections in six patients with myasthenia gravis. The drug caused improvement of muscle strength and neuromuscular transmission as demonstrated by clinical observations and repetitive electrical nerve stimulation. The drug was effective in cases without any other treatment as well as in cases undergoing treatment with anticholinesterases. It is concluded that 4-aminopyridine may be of value as a supplementary drug in the treatment of myasthenia gravis

Topics: Research Article
Year: 1979
DOI identifier: 10.1136/jnnp.42.2.171
OAI identifier: oai:pubmedcentral.nih.gov:490183
Provided by: PubMed Central
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