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Endocarditis caused by Rhodotorula successfully treated with 5-fluorocytosine.

By Y Naveh, A Friedman, D Merzbach and N Hashman

Abstract

A 7-year-old boy suffering from aortic regurgitation and mitral stenosis and regurgitation was admitted with endocarditis caused by Rhodotorula pilimanae and was treated successfully with orally administered antifungal agent, namely 5-fluorocytosine (5-FC). A dose of 100 mg per kg body weight, divided into four equal parts, was prescribed. After a prolonged febrile period his temperature dropped to normal on the fourth day of 5-FC therapy. Review of the published reports disclosed few cases of endocarditis due to Rhodotorula spp. and this case seems to be the first treated with 5-FC. Follow-up in one year, after discharge from the hospital, revealed no evidence of relapse

Topics: Research Article
Year: 1975
DOI identifier: 10.1136/hrt.37.1.101
OAI identifier: oai:pubmedcentral.nih.gov:484161
Provided by: PubMed Central
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