Article thumbnail
Location of Repository

The antithrombin activity of glucuronic esters of bilirubin

By M. Kopeć, T. Darocha, S. Niewiarowski and J. Stachurska


The plasma of patients with pronounced jaundice as well as that of cats with experimental obstructive jaundice inhibits the clotting of normal plasma with thrombin. The influence of different bile constituents—bilirubin, bilirubin glucuronides, sodium salts of bile acid—on the clotting of plasma or fibrinogen with thrombin was examined. Bilirubin glucuronides in concentrations above 8 mg.% showed antithrombic activity but other substances were inactive. Glucuronic acid and phenolphthalein glucuronide in concentrations up to 100 mg.% did not have any influence on the thrombin time

Topics: Articles
Year: 1961
DOI identifier: 10.1136/jcp.14.5.478
OAI identifier:
Provided by: PubMed Central
Sorry, our data provider has not provided any external links therefore we are unable to provide a link to the full text.

Suggested articles

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.