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Cyclic Thymineless Death Significantly Increases Frequency of R-Plasmid Elimination

By M. J. Tribe and R. J. Pinney

Abstract

Thymine starvation of Escherichia coli strain C600 thy (R46) eliminated the R plasmid at a frequency of 17%. This was increased fourfold, to 68%, after the same culture was subjected to an additional three cycles of growth followed by thymineless death

Topics: Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Year: 1977
DOI identifier: 10.1128/aac.12.4.555
OAI identifier: oai:pubmedcentral.nih.gov:429968
Provided by: PubMed Central
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