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Comparison of Direct and Standardized Disk Diffusion Susceptibility Testing of Urine Cultures

By Gary E. Hollick and John A. Washington


A comparison between direct and standardized disk diffusion tests was made on a total of 300 urine specimens containing ≥10(5) organisms/ml. Of these, 246 represented pure cultures and 54 represented mixed cultures. The number of major discrepancies per organism tested in pure culture was 18 (7.3%) and in mixed cultures it was 23 (42.6%). The percentage of major discrepancies per total number of antimicrobial drug comparisons made was 1.4%. Although this procedure may be of value in selected cases with pure cultures of organisms present in quantities ≥10(5)/ml, its use on a routine basis is not recommended

Topics: Physiological Effects and Microbial Susceptibility
Year: 1976
DOI identifier: 10.1128/aac.9.5.804
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Provided by: PubMed Central
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