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Multivariate Analysis of Cytokine Responses Identifies Distinctive Sensitivities to Lipopolysaccharide in Humans

By David D. Duncan, Lorrie Tiberio and John H. Eldridge

Abstract

We describe methods to identify high and low responders in a whole-blood assay of lipopolysaccharide-stimulated cytokine responses. Two multivariate measures of the cytokine responses both captured high and low responses for each of the four individual cytokines that were assayed

Topics: Host Response and Inflammation
Publisher: American Society for Microbiology
Year: 2004
DOI identifier: 10.1128/IAI.72.7.4282-4285.2004
OAI identifier: oai:pubmedcentral.nih.gov:427430
Provided by: PubMed Central
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