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Microsurgically Fused Human Somatic Cell Hybrids: Analysis and Cloning

By Elaine G. Diacumakos

Abstract

Cell fusion by microsurgery permits production of specified bicellular hybrid cells with very high efficiency. Systematic analysis of the fate of bicellular hybrids reveals fundamental properties of cells in accordance with cell type. Bicellular hybrids that do not proliferate survive 1-21 days; those that do proliferate form clones 8-9 days after fusion

Topics: Biological Sciences: Cell Biology
Year: 1973
DOI identifier: 10.1073/pnas.70.12.3382
OAI identifier: oai:pubmedcentral.nih.gov:427241
Provided by: PubMed Central
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