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Inhibition of Certain Deoxyribonucleic Acid Viruses by Liver Extracts

By Helen H. Lee and T. W. Tinsley


A proteinaceous substance was detected in the liver of several animal species that inhibited the multiplication of certain deoxyribonucleic acid, but not ribonucleic acid, viruses. Preliminary experiments suggested that its site of action was not extracellular. It did not inhibit virus by interfering with adsorption to cells. It was suggested that this inhibiting substance acts directly upon cells by interfering with viral synthesis

Topics: Pathogenic Mechanisms, Ecology, and Epidemiology
Year: 1972
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Provided by: PubMed Central
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