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Ganglioside and rabbit erythrocyte membrane receptor for staphylococcal alpha-toxin.

By I Kato and M Naiki


The hemolytic activity of staphylococcal alpha-toxin is inhibited by an N-acetylglucosamine-containing ganglioside (GlcNAc-ganglioside) but not by any of the related glycolipids. The GlcNAc-ganglioside also is precipitated with the toxin by a gel-diffusion technique. It is postulated that GlcNAc-ganglioside may be the membrane receptor for the alpha-toxin

Topics: Research Article
Year: 1976
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Provided by: PubMed Central
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