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The motilin receptor agonist erythromycin stimulates hunger and food intake through a cholinergic pathway

By Eveline Deloose, Rita Vos, Pieter Janssen, Omer Van den Bergh, Lukas Van Oudenhove, Inge Depoortere and Jan Tack


Motilin-induced phase III contractions have been identified as a hunger signal. These phase III contractions occur as part of the migrating motor complex (MMC), a contractility pattern of the gastrointestinal tract during fasting. The mechanism involved in this association between subjective hunger feelings and gastrointestinal motility during the MMC is largely unknown, however, as is its ability to stimulate food intake.status: publishe

Publisher: Journal of Clinical Nutrition
Year: 2016
DOI identifier: 10.3945/ajcn.115.113456
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Provided by: Lirias
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