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Hipoglikemijski i antioksidativni učinak ekstrakta kore kineskog cimeta (Cinnamomum cassia Blume)

By Zdenka Kalođera, Marijana Zovko Končić, Ratimir Klepac, Betilija Fadi, Darija Kajtar and Tatjana Šešok


Chinese cinnamon (Cinnamomum cassia Btume, Lauraceae) is evergreen tree originating from China. The aim of presented research was to evaluate hypoglycemic and antioxidant properties of Chinese cinnamon bark extract. Antioxidant activity in vitro was investigated by four methods: antiradical and chelating activity, reducing power and activity in /3-carotene-linoleate assay. Diabetes in rats was induced by intraperitoneal injection of streptozotocin. Glucose bloocl level, as well as some parameters of oxidative stress in erythrocite and plasma (superoxide radical, lipid peroxidation, carbonylatecl proteins) were determined. Chinese cinnamon bark extract clemonstrated significanr in vitro antioxiclant activity. Chelating activity of the extract was equal to the activity of EDTA ancl greater than the activity of quercetin, while the activity of extract in /3-carotene-linoleate assay was greater than the activity of butylated hyclroxyanisole. Moreover, blood glucose level in rats treatecl with Chinese cinnamon was lower than in untreated rats. The indicators of oxidative stress were also lowerecl. The results indicate that Chinese cinnamon bark extract might be helpful in treatment of hyperglycemia and secondary complications of type 2 diabetes

Topics: kineski cimet, Cinnamomum cassia Blume, kora kineskog cimeta, antioksidativno djelovanje, glukoza, BIOMEDICINA I ZDRAVSTVO. Farmacija. Farmacija., BIOMEDICINE AND HEALTHCARE. Pharmacy. Pharmacy.
Year: 2010
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