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Neurotensin is a versatile modulator of in vitro human pancreatic ductal adenocarcinoma cell (PDAC) migration.

By Tatjana Mijatovic, Philippe Gailly, Véronique Mathieu, Nancy De Nève, Paul Yeaton, Robert Kiss and Christine Decaestecker

Abstract

While the neurotensin (NT) roles in pancreatic cancer growth are well documented, its effects on pancreatic cancer cell migration have not been described

Topics: Actins - metabolism, Carcinoma, Pancreatic Ductal - pathology, Models, Biological, Neurotensin - pharmacology, Protein Subunits - metabolism, Receptors, Neurotensin - metabolism, Signal Transduction - drug effects, Vitronectin - metabolism, cdc42 GTP-Binding Protein - metabolism, rac1 GTP-Binding Protein - metabolism, rho GTP-Binding Proteins - metabolism, Cell Adhesion - drug effects, Cell Line, Tumor, Cell Movement - drug effects, Cytoskeleton - drug effects, metabolism, Enzyme Activation - drug effects, Humans, Integrin alphaV - metabolism, Integrin beta Chains - metabolism
Publisher: I O S Press
Year: 2007
OAI identifier: oai:dial.uclouvain.be:boreal:112780
Provided by: DIAL UCLouvain
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