Skip to main content
Article thumbnail
Location of Repository

Quality control of moxalactam susceptibility disks.

By A L Barry, D A Preston, R N Jones, T L Gavan and C Thornsberry


In vitro evaluation of two types of moxalactam disks revealed significant performance differences when Staphylococcus aureus was being tested. The differences were traced to the amount of decarboxylated moxalactam present in the disks. The decarboxylated analog was much more active than the parent compound against S. aureus, not active against Pseudomonas aeruginosa, and approximately as active as the parent compound against Escherichia coli. A nine-laboratory coordinated study was performed to establish quality control parameters for 30-micrograms moxalactam disks. Problems with the establishment of interpretive standards for moxalactam disk tests were evaluated in the light of differences between disks utilized in earlier studies and those that are now commercially available. The type of disk greatly influences standards for tests with S. aureus but has insignificant influence on testing gram-negative bacilli

Topics: Research Article
Year: 1983
OAI identifier:
Provided by: PubMed Central
Sorry, our data provider has not provided any external links therefore we are unable to provide a link to the full text.

Suggested articles

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.