Location of Repository

A determinant of polyomavirus virulence enhances virus growth in cells of renal origin.

By J B Bolen, S E Fisher, K Chowdhury, T C Shan, J E Williams, C J Dawe and M A Israel

Abstract

We have identified a strain of polyomavirus, Py(L), which is unusual in causing acute morbidity and early death after inoculation of newborn mice. We determined that these animals died of kidney failure associated with extensive, virus-mediated destruction of renal tissue. Interestingly, the Py(L) strain infects baby mouse kidney cell cultures more efficiently than do other strains

Topics: Research Article
Year: 1985
OAI identifier: oai:pubmedcentral.nih.gov:255049
Provided by: PubMed Central
Sorry, our data provider has not provided any external links therefore we are unable to provide a link to the full text.

Suggested articles


To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.