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Monoclonal antibody-mediated neutralization of infectious human papillomavirus type 11.

By N D Christensen, J W Kreider, N M Cladel, S D Patrick and P A Welsh


Monoclonal antibodies recognizing human papillomavirus type 11 (HPV-11) were prepared from BALB/c mice immunized with intact HPV-11 virions obtained from morphologically transformed human foreskin xenografts grown subrenally in athymic mice. Four of five monoclonal antibodies that were reactive by enzyme-linked immunosorbent assay only to intact virions neutralized HPV-11 infectivity in the athymic mouse xenograft system

Topics: Research Article
Year: 1990
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Provided by: PubMed Central
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