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Characterization of Three Plasmid Deoxyribonucleic Acid Molecules in a Strain of Streptococcus faecalis: Identification of a Plasmid Determining Erythromycin Resistance

By D. B. Clewell, Y. Yagi, G. M. Dunny and S. K. Schultz

Abstract

Three plasmids designated α, β, and γ, distinguishable by their molecular weights (6, 17, and 34 million, respectively) were isolated from Streptococcus faecalis strain DS-5 (ATCC 14508). Derivatives of this strain “cured” for erythromycin resistance lacked the β-plasmid. In the parent strain the β-plasmid was estimated to be present to the extent of one to two copies per chromosomal genome equivalent whereas the α- and γ-plasmids were about nine and five copies, respectively

Topics: Genetics and Molecular Biology
Year: 1974
OAI identifier: oai:pubmedcentral.nih.gov:246555
Provided by: PubMed Central
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