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Inactivation of poliovirus and other enteroviruses by solutions of sodium fluoride at low pH.

By R D Eubanks and S R Farrah

Abstract

Solutions of sodium fluoride at pH 3 to 4 inactivated enteroviruses, whereas other sodium salts had little or no effect on virus infectivity. Solutions of potassium fluoride also inactivated viruses under similar conditions. Light, temperature, and the presence of organic compounds such as detergents and fecal matter did not affect inactivation of virus by 0.4 M solutions of sodium fluoride at pH 3. to 4. Decreasing the sodium fluoride concentration below 0.04 M or raising the pH above 4 reduced the viricidal properties of the solutions. Virus adsorbed to membrane filters and sludge flocs could not be recovered after treatment of solids-associated virus with solutions of sodium fluoride

Topics: Research Article
Year: 1981
OAI identifier: oai:pubmedcentral.nih.gov:243760
Provided by: PubMed Central
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