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Inhibition of Dictyostelium discoideum beta-glucosidase by purines.

By R W Parish


beta-Glucosidase of Dictyostelium discoideum is inhibited by purines in the following order: adenine greater than adenosine greater than 6-methylaminopurine greater than hypoxanthine greater than inosine greater than purine greater than guanosine. Adenine inhibits activity by 50% at 1 to 2 mM. The kinetics are complex because the enzyme is stimulated by substrate and inhibited by glucose

Topics: Research Article
Year: 1977
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Provided by: PubMed Central
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