Skip to main content
Article thumbnail
Location of Repository

Decreased elastin in vessel walls puts the pressure on

By Jeanine D’Armiento

Abstract

Mice haploinsufficient for elastin develop structural changes in vessel walls similar to those seen in patients with mutations in the elastin gene. A new study demonstrates that due to mechanical changes in the vessel wall, these animals exhibit increased mean arterial pressures. The results evoke the possibility that alterations in elastin may contribute to the development of essential hypertension in patients

Topics: Commentary
Publisher: American Society for Clinical Investigation
Year: 2003
DOI identifier: 10.1172/JCI200320226
OAI identifier: oai:pubmedcentral.nih.gov:228487
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://dx.doi.org/10.1172/JCI2... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.