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AMINOACYL-TRNA SYNTHETASE REACTION UNIQUE TO EARLY EMBRYONIC TISSUE OF THE MOUSE*

By Owen M. Rennert

Abstract

The formation of trifluoroleucine-tRNA and leucine-tRNA during embryonic development of the mouse is a function of gestational age. The existence of a leucine-tRNA synthetase has been demonstrated in early embryonic tissue (gestational age <10 days) which has unique chemical properties, acylating tRNA with trifluoroleucine with avidity almost equal to leucine. This enzyme has been shown to be stable to heating at 45°C for 30 minutes

Topics: Biological Sciences: Biochemistry
Year: 1969
OAI identifier: oai:pubmedcentral.nih.gov:223534
Provided by: PubMed Central
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