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HOMOLOGY OF Pseudomonas CYTOCHROME c-551 WITH EUKARYOTIC c-CYTOCHROMES

By Saul B. Needleman and Terence T. Blair

Abstract

The homology of Pseudomonas cytochrome c-551 with eukaryotic cytochromes c is examined with a computer-based procedure devised to determine whether similarities exist between these proteins. One method is given by which the more recently evolved cytochromes c might have arisen from the Pseudomonas protein. This procedure involves only common genetic phenomena and accounts for most of the structural differences between the bacterial and mammalian cytochromes. A time-scale relationship between the c-cytochromes from several microorganisms, a mold, yeast, and the eukaryotic organisms is proposed

Topics: Biological Sciences: Biochemistry
Year: 1969
OAI identifier: oai:pubmedcentral.nih.gov:223454
Provided by: PubMed Central
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