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Properties and biosynthesis of cyclopropane fatty acids in Escherichia coli.

By J E Cronan, R Reed, F R Taylor and M B Jackson

Abstract

The lipid phase transition of Escherichia coli phospholipids containing cyclopropane fatty acids was compared with the otherwise homologous phospholipids lacking cyclopropane fatty acids. The phase transitions (determined by scanning calorimetry) of the two preparations were essentially identical. Infection of E. coli with phage T3 inhibited cyclopropane fatty acid formation over 98%, whereas infection with mutants which lack the phage coded S-adenosylmethionine cleavage enzyme had no effect on cyclopropane fatty acid synthesis. These data indicate that S-adenosylmethionine is the methylene in cyclopropane fatty acid synthesis

Topics: Research Article
Year: 1979
OAI identifier: oai:pubmedcentral.nih.gov:218246
Provided by: PubMed Central
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