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DNA damage-inducible loci in Salmonella typhimurium.

By C M Smith, Z Arany, C Orrego and E Eisenstadt


lac operon fusions to DNA damage-inducible (din) loci were generated in Salmonella typhimurium LT2. Many of these din fusions were efficiently repressed by cloned Escherichia coli LexA, while others were not; all required RecA for induction. Several din fusions exhibited strong inducibility and will be useful in developing an SOS induction assay in S. typhimurium to detect genotoxins

Topics: Research Article
Year: 1991
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Provided by: PubMed Central
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