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Inhibition of cell division initiation by an imbalance in the ratio of FtsA to FtsZ.

By S J Dewar, K J Begg and W D Donachie

Abstract

Elevated levels of FtsA protein block cell division at a very early stage, similar to that caused by inhibition of the action of FtsZ. In contrast, overexpression of FtsA and FtsZ together does not block division. A specific ratio of FtsA to FtsZ protein, therefore, is required for cell division

Topics: Research Article
Year: 1992
DOI identifier: 10.1128/jb.174.19.6314-6316.1992
OAI identifier: oai:pubmedcentral.nih.gov:207705
Provided by: PubMed Central
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