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A pneumococcal clinical isolate with high-level resistance to cefotaxime and ceftriaxone.

By A M Figueiredo, J D Connor, A Severin, M V Vaz Pato and A Tomasz


A beta-lactam-resistant serotype 23F Streptococcus pneumoniae clinical isolate from the cerebrospinal fluid of a pediatric patient from California is unusual in that the MICs of cefotaxime and ceftriaxone (2.5 micrograms/ml each) are higher than that of benzylpenicillin (0.3 micrograms/ml); the isolate also has patterns of penicillin-binding proteins and of cell wall peptides which are atypical compared with those of previously examined penicillin-resistant pneumococci

Topics: Research Article
Year: 1992
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Provided by: PubMed Central
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