Article thumbnail
Location of Repository

Minimal Introns Are Not “Junk”

By Jun Yu, Zhiyong Yang, Miho Kibukawa, Marcia Paddock, Douglas A. Passey and Gane Ka-Shu Wong

Abstract

Intron-size distributions for most multicellular (and some unicellular) eukaryotes have a sharp peak at their “minimal intron” size. Across the human population, these minimal introns exhibit an abundance of insertion-deletion polymorphisms, the effect of which is to maintain their optimal size. We argue that minimal introns affect function by enhancing the rate at which mRNA is exported from the cell nucleus

Topics: Letter
Publisher: Cold Spring Harbor Laboratory Press
Year: 2002
DOI identifier: 10.1101/gr.224602
OAI identifier: oai:pubmedcentral.nih.gov:186636
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://dx.doi.org/10.1101/gr.2... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.