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Identification, sequencing, and enzymatic activity of the erythrose-4-phosphate dehydrogenase gene of Vibrio cholerae.

By P A Carroll, G Zhao, S A Boyko, M E Winkler and S B Calderwood


We have identified a gene in Vibrio cholerae (epd) which encodes an erythrose-4-phosphate dehydrogenase activity and is located immediately downstream of an iron-regulated virulence gene, irgA, and immediately upstream of a gene encoding phosphoglycerate kinase (pgk). Expression of epd in V. cholerae is not regulated by iron, nor is it required for virulence in an infant mouse model

Topics: Research Article
Year: 1997
DOI identifier: 10.1128/jb.179.1.293-296.1997
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Provided by: PubMed Central
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