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Outer membrane permeation of Bacteroides fragilis by cephalosporins.

By A Yotsuji, J Mitsuyama, R Hori, T Yasuda, I Saikawa, M Inoue and S Mitsuhashi


Outer membrane permeation of Bacteroides fragilis by cephalosporins was examined by a previously described method. The permeation parameters of cephalosporins in B. fragilis were close to 10(-5) cm3/min per microgram of cell dry weight. These values were about an order of magnitude lower than those in Escherichia coli. In B. fragilis, the permeation was not directly proportional to the hydrophilicity of cephalosporins, and the ion selectivity was weak

Topics: Research Article
Year: 1988
DOI identifier: 10.1128/aac.32.7.1097
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Provided by: PubMed Central
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