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The enigma of sepsis

By Niels C. Riedemann, Ren-Feng Guo and Peter A. Ward


Sepsis remains a serious cause of morbidity and mortality, and the pathophysiology of the disease is not clear. The definition of the clinical manifestations of sepsis is ever evolving. This review discusses the search for effective therapeutic interventions, hurdles in translational sepsis research, and new therapies in development in current clinical trials

Topics: Science in Medicine
Publisher: American Society for Clinical Investigation
Year: 2003
DOI identifier: 10.1172/JCI200319523
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Provided by: PubMed Central
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