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Emerging Extended-Spectrum β-Lactamases in Proteus mirabilis

By Laura Pagani, Roberta Migliavacca, Lucia Pallecchi, Cecilia Matti, Ernesto Giacobone, Gianfranco Amicosante, Egidio Romero and Gian Maria Rossolini


β-Lactamase production was detected in 147 (52%) of 282 consecutive nonduplicate Proteus mirabilis isolates obtained over a 1-year period from the S. Matteo Hospital of Pavia (northern Italy). Seventy isolates (48% of the β-lactamase producers) were found to produce extended-spectrum β-lactamases (ESBLs), identified as PER-1 (first report in this species) and TEM-52 in 52 and 18 isolates, respectively. Analysis of clonal diversity of the ESBL producers suggested different spreading patterns for the two ESBL determinants

Topics: Bacteriology
Publisher: American Society for Microbiology
Year: 2002
DOI identifier: 10.1128/JCM.40.4.1549-1552.2002
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Provided by: PubMed Central
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