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In Vitro Activities of Investigational Triazoles against Fusarium Species: Effects of Inoculum Size and Incubation Time on Broth Microdilution Susceptibility Test Results

By Niki I. Paphitou, Luis Ostrosky-Zeichner, Victor L. Paetznick, Jose R. Rodriguez, Enuo Chen and John H. Rex

Abstract

We studied the effects of inoculum size and incubation time on the susceptibility testing results for various antifungal agents against 22 Fusarium isolates by the NCCLS microdilution method. Increased inoculum size and extended incubation time resulted in elevated MICs. Posaconazole and voriconazole exhibited promising antifungal activities

Topics: Susceptibility
Publisher: American Society for Microbiology
Year: 2002
DOI identifier: 10.1128/AAC.46.10.3298-3300.2002
OAI identifier: oai:pubmedcentral.nih.gov:128790
Provided by: PubMed Central
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