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Molecular Characterization of the vanE Gene Cluster in Vancomycin-Resistant Enterococcus faecalis N00-410 Isolated in Canada

By D. A. Boyd, T. Cabral, P. Van Caeseele, J. Wylie and M. R. Mulvey


The vanE operon was characterized from Enterococcus faecalis N00-410 (MIC of vancomycin = 24 μg/ml). The organization of the vanE operon was identical to that of the vanC1 operon from Enterococcus gallinarum, with protein identities ranging from 46 to 63%. An open reading frame located downstream of the vanE operon showed significant homology to a number of integrase genes, all of which are located downstream of the chromosomal GMP synthase gene guaA

Topics: Mechanisms of Resistance
Publisher: American Society for Microbiology
Year: 2002
DOI identifier: 10.1128/AAC.46.6.1977-1979.2002
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Provided by: PubMed Central
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