Skip to main content
Article thumbnail
Location of Repository

Aquatic Insects as a Vector for Mycobacterium ulcerans

By Laurent Marsollier, Raymond Robert, Jacques Aubry, Jean-Paul Saint André, Henri Kouakou, Pierre Legras, Anne-Lise Manceau, Chetaou Mahaza and Bernard Carbonnelle

Abstract

Mycobacterium ulcerans is an emerging environmental pathogen which causes chronic skin ulcers (i.e., Buruli ulcer) in otherwise healthy humans living in tropical countries, particularly those in Africa. In spite of epidemiological and PCR data linking M. ulcerans to water, the mode of transmission of this organism remains elusive. To determine the role of aquatic insects in the transmission of M. ulcerans, we have set up an experimental model with aquariums that mimic aquatic microenvironments. We report that M. ulcerans may be transmitted to laboratory mice by the bite of aquatic bugs (Naucoridae) that are infected with this organism. In addition, M. ulcerans appears to be localized exclusively within salivary glands of these insects, where it can both survive and multiply without causing any observable damage in the insect tissues. Subsequently, we isolated M. ulcerans from wild aquatic insects collected from a zone in the Daloa region of Ivory Coast where Buruli ulcer is endemic. Taken together, these results point to aquatic insects as a possible vector of M. ulcerans

Topics: Public Health Microbiology
Publisher: American Society for Microbiology
Year: 2002
DOI identifier: 10.1128/AEM.68.9.4623-4628.2002
OAI identifier: oai:pubmedcentral.nih.gov:124085
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://dx.doi.org/10.1128/AEM.... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.