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Accurate, Noninvasive Detection of Helicobacter pylori DNA from Stool Samples: Potential Usefulness for Monitoring Treatment

By Anthony P. Shuber, Jennifer J. Ascaño, Kevin A. Boynton, Anastasia Mitchell, Henry F. Frierson, Wa’el El-Rifai and Steven M. Powell

Abstract

A novel DNA assay demonstrating sensitive and accurate detection of Helicobacter pylori from stool samples is reported. Moreover, in three individuals tested for therapeutic response, the assay showed the disappearance of H. pylori DNA during treatment. Thus, this noninvasive molecular biology-based assay has the potential to be a powerful diagnostic tool given its ability to specifically identify H. pylori DNA

Topics: Bacteriology
Publisher: American Society for Microbiology
Year: 2002
DOI identifier: 10.1128/JCM.40.1.262-264.2002
OAI identifier: oai:pubmedcentral.nih.gov:120120
Provided by: PubMed Central
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