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Central effects of clozapine in regulating micturition in anesthetized rats

By Pedro L Vera, Alejandro J Miranda-Sousa, Raul C Ordorica and Irving Nadelhaft
Topics: Research Article
Publisher: BioMed Central
Year: 2002
DOI identifier: 10.1186/1471-2210-2-6
OAI identifier:
Provided by: PubMed Central

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  1. (1986). A: Analysis of factors involved in determining urinary bladder voiding cycle in urethan-anesthetized rats.
  2. (1996). Andersson K-E: Role of spinal and peripheral alpha2 adrenoceptors in micturition in conscious rats.
  3. (2000). Basic statistics for the behavioural sciences
  4. (1993). BM: Tissue concentrations of clozapine and its metabolites in the rat. Neuropsychopharmacology
  5. (1997). Brescan DW: Incidence of risperidone induced incontinence. Schizophrenia research
  6. (1998). Breyer-Pfaff U: Pharmacokinetics of clozapine and its metabolites in psychiatric patients: plasma protein binding and renal clearance.
  7. (1993). Clozapine and N-desmethylclozapine are potent 5-HT1c receptor antagonists.
  8. (1998). Constantinou CE: Effect of α 1 adrenoceptor antagonism on the urodynamics of the upper and lower urinary tract of the male rat. Neurourology and Urodynamics
  9. (1993). de Groat WC: Changes in bladder and external urethral sphincter function after spinal cord injury in the rat.
  10. (1998). Deutch AY: Effects of desmethylclozapine on fos protein expression in the forebrain: in vivo biological activity of the clozapine metabolite. Neuropsychopharmacology
  11. (1984). Experimental evidence for a central nervous system site of action in the effect of alphaadrenergic blockers on the external urethral sphincter.
  12. (2001). Groat de WC: Central muscarinic mechanisms regulating voiding in rats. JPET
  13. (1999). Hiemke C: Distribution of clozapine and desmethylclozapine between blood and brain in rats. Eur Neuropsychopharmacol
  14. (2000). Influences of external urethral sphincter relaxation induced by alpha-bungarotoxin, a neuromuscular junction blocking agent, on voiding dysfunction in the rat with spinal cord injury. Urology
  15. (1994). JG: Clozapine and metabolites: concentration in serum and clinical findings during treatment of chronically psychotic patients.
  16. (2000). JG: The role of spinal and peripheral α 1- and α 2-adrenoceptors on bladder activity induced by bladder distension in anaesthetized rat.
  17. (1996). JM: Bladder dysfunction associated with clozapine therapy.
  18. (1995). KB: Pharmacological analysis of the noradrenergic control of central sympathetic and somatic reflexes controlling the lower urinary tract in the anesthetized rat.
  19. (2000). KM: Olanzapine-induced urinary incontinence: treatment with ephedrine.
  20. (1998). Maximizing clozapine therapy: managing side effects.
  21. (2001). Nadelhaft I: Clozapine inhibits micturition parameters and the external urethral sphincter during cystometry in anesthetized rats.
  22. (2001). Nadelhaft I: Effects of the atypical neuroleptics clozapine on micturition parameters in anesthetized rats. Neurourol Urodyn
  23. (2001). Nadelhaft I: Effects of two atypical neuroleptics, olanzapine and risperidone, on the function of the urinary bladder and the external urethral sphincter in anesthetized rats.
  24. (1996). PE: Clozapine-induced urinary incontinence: incidence and treatment with ephedrine.
  25. (1996). Risperidone-induced ejaculatory and urinary dysfunction.
  26. (1996). Side effect profiles of new antipsychotic agents.
  27. (2000). Souder T: Binding of antipsychotic drugs to human brain receptors. Focus on newer generation compounds. Life Sciences
  28. (1999). T-H: A retrospective study of clozapine and urinary incontinence in Chinese in-patients. Acta Psychiatr Scand
  29. (1976). TA: Chronic catheterization of the spinal subarachnoid space. Physiol Behav
  30. (1986). The Rat Brain in Stereotaxic Coordinates
  31. (1995). Thor KB: Inhibition of central sympathetic and somatic outflow to the lower urinary tract of the cat by the alpha1 adrenergic receptor antagonist prazosin.
  32. (2000). Urinary incontinence with risperidone.
  33. (1990). WC: Pontine control of the urinary bladder and external urethral sphincter in the rat. Brain Research
  34. (1996). Wong DT: Radioreceptor binding profile of the atypical antipsychotic olanzapine. Neuropsychopharmacology

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