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Spontaneous Formation of a Mannitol-Producing Variant of Leuconostoc pseudomesenteroides Grown in the Presence of Fructose

By Gert J. Grobben, Sjors W. P. G. Peters, H. Wouter Wisselink, Ruud A. Weusthuis, Marcel H. N. Hoefnagel, Jeroen Hugenholtz and Gerrit Eggink


We report the spontaneous formation of a stable mannitol-producing variant of Leuconostoc pseudomesenteroides. The mannitol-producing variant showed mannitol dehydrogenase activity which was absent in the parental strain. It was also able to use fructose and glucose simultaneously, whereas the parental strain showed diauxic growth with these sugars. A possible explanation of these observations is discussed

Topics: Physiology and Biotechnology
Publisher: American Society for Microbiology
Year: 2001
DOI identifier: 10.1128/AEM.67.6.2867-2870.2001
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Provided by: PubMed Central
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