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Activation of Pyridinium Salts for Electrophilic Acylation: a Method for Conversion of Pyridines into 3-Acylpyridines

By A. Klapars and E. Vedejs

Abstract

Cyanide adducts of N-MOM pyridinium salts react with strong acylating reagents to provide 3-acyl-4-cyano-1,4-dihydropyridines that can be aromatized to 3-acylpyridines using ZnCl 2 in refluxing ethanol

Publisher: Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media
Year: 2004
DOI identifier: 10.1023/B:COHC.0000040772.13427.0b
OAI identifier: oai:deepblue.lib.umich.edu:2027.42/41517
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