Tivantinib (ARQ 197) affects the apoptotic and proliferative machinery downstream of c-MET: role of Mcl-1, Bcl-xl and Cyclin B1
Abstract
Abstract is not available.- info:eu-repo/semantics/article
- HCC; apoptosis; c-MET; targeted therapies; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cholangiocarcinoma; Colorectal Neoplasms; Cyclin B1; Hep G2 Cells; Humans; Liver Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Pancreatic Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyrrolidinones; Quinolines; bcl-X Protein
- HCC
- apoptosis
- c-MET
- targeted therapies
- Apoptosis
- Carcinoma
- Hepatocellular
- Cell Line
- Tumor
- Cell Proliferation
- Cholangiocarcinoma
- Colorectal Neoplasms
- Cyclin B1
- Hep G2 Cells
- Humans
- Liver Neoplasms
- Myeloid Cell Leukemia Sequence 1 Protein
- Pancreatic Neoplasms
- Protein Kinase Inhibitors
- Proto-Oncogene Proteins c-met
- Pyrrolidinones
- Quinolines
- bcl-X Protein