An Analysis of Drug Dissolution Rates in the USP 24 Type 2 Apparatus

McDonnell, David; Redmond, Brendan; D\u27Arcy, Deirdre M; Healy, Anne Marie; Corrigan, Owen

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An Analysis of Drug Dissolution Rates in the USP 24 Type 2 Apparatus

Authors: David McDonnell
Brendan Redmond
Deirdre M D\u27Arcy
Anne Marie Healy
Owen Corrigan
Publication date: January 1, 2009
Publisher: Technological University Dublin

Abstract

This paper applies boundary layer theory to the process of drug dissolution in the USP 24, Type 2 Apparatus. The mass transfer rate from the top flat surface of a compact in various positions within the device is evaluated by means of a Pohlhausen integral method

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