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Effectiveness of a brief cognitive-behavioural therapy intervention in the treatment of schizophrenia

By Douglas Turkington, David Kingdon and Trevor Turner


Declaration of interest: Funding was provided by Pfizer Ltd.<br/>Background: Little evidence exists to indicate whether community psychiatric nurses can achieve the results reported by expert cognitive—behavioural therapists in patients with schizophrenia.<br/>Aims: To assess the effectiveness and safety of a brief cognitive—behavioural therapy (CBT) intervention in a representative community sample of patients with schizophrenia in secondary care settings.<br/>Method: A pragmatic randomised trial was performed involving 422 patients and carers to compare a brief CBT intervention against treatment as usual.<br/>Results: Patients who received CBT (n=257) improved in overall symptomatology (P=0.015; number needed to treat [NNT]=13), insight (P&lt;0.001; NNT=10) and depression (P=0.003; NNT=9) compared with the controlgroup (n=165). Insight was clinically significantly improved (risk ratio=1.15, 95% CI 1.01-1.31). There was no increase in suicidal ideation.<br/>Conclusions: Community psychiatric nurses can safely and effectively deliver a brief CBT intervention to patients with schizophrenia and their carers

Topics: RT, RC0321, RM
Year: 2002
OAI identifier: oai:eprints.soton.ac.uk:40635
Provided by: e-Prints Soton
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